Human Epidermal Neural Crest Stem Cells (hEPI-NCSC): Characterization and Directed Differentiation into Osteocytes and Melanocytes

March 2011 in “ Stem Cell Reviews and Reports ”

Oliver Clewes, Alla Narytnyk, Kevin R. Gillinder, Andrew Loughney, Alison Murdoch, Maya Sieber‐Blum

human epidermal neural crest stem cells hEPI-NCSC hair follicles bulge multipotency self-renewal neural crest derivatives osteocytes melanocytes pluripotency genes autologous transplantation cell-based therapies regenerative medicine ex vivo expansion stem cells hair follicle bulge cell therapy regenerative treatment

Studysummary This article describes protocols for isolating and expanding human epidermal neural crest stem cells and discusses their potential for cell-based therapies in regenerative medicine, but reports no new clinical results.

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