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    Whole Genome Sequencing Analysis of Alpaca Suggests TRPV3 as a Candidate Gene for the Suri Phenotype

    February 2024 in “ BMC genomics ”
    Stefano Pallotti, Matteo Picciolini, Giovanni Deiana … C. Renieri
    Studysummary This study identified a gene variant in the TRPV3 gene that may explain the suri alpaca phenotype, characterized by longer and less crimped fleece, suggesting this variant's involvement in the development of these hair characteristics compared to the huacaya phenotype.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
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    Research cited in this study 7

    1. TRPV3 Ion Channel: From Gene to Pharmacology International Journal of Molecular Sciences · 2023
    2. Hair Loss Caused by Gain-of-Function Mutant TRPV3 Is Associated with Premature Differentiation of Follicular Keratinocytes ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2021
    3. Using WGCNA to Identify Hub Genes of Skin Hair Follicle Development in Fetal Stage of Inner Mongolia Cashmere Goat PloS one · 2020
    4. Comparative Transcriptome Analysis of Fetal Skin Reveals Key Genes Related to Hair Follicle Morphogenesis in Cashmere Goats PLoS ONE · 2016
    5. Activation of Transient Receptor Potential Vanilloid-3 Inhibits Human Hair Growth ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2011
    6. Hair Follicle Characteristics and Fiber Production in South American Camelids Animal · 2010
    7. Influence of TRPV3 Mutation on Hair Growth Cycle in Mice Biochemical and Biophysical Research Communications · 2007