A Systematic Review on the Treatment of Pediatric Severe Alopecia Areata by Topical Immunotherapy, Anthralin, or Low-Level Light/Laser Therapy: Focus on Efficacy, Safety, Treatment Duration, Recurrence, and Follow-Up Based on Clinical Studies

    October 2021 in “ Journal of Cosmetic Dermatology ”
    Elham Behrangi, Masoumeh Roohaninasab, Afsaneh Sadeghzadeh‐Bazargan … Milad Dodangeh
    Studysummary This review found that topical immunotherapy and light/laser therapy may achieve over 50% hair regrowth efficacy in treating extensive alopecia areata in children, with no serious side effects observed.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
    Read the full study on doi.org →
    Discuss this study in the Community →

    Research cited in this study 23

    1. Systematic Review of Platelet-Rich Plasma in Treating Alopecia: Focusing on Efficacy, Safety, and Therapeutic Durability Dermatologic Therapy · 2021
    2. A Systematic Review of the Effect of Platelet-Rich Plasma on Androgenetic Alopecia in Women Dermatologic Therapy · 2020
    3. Photobiomodulation for the Management of Alopecia: Mechanisms of Action, Patient Selection, and Perspectives Clinical, Cosmetic and Investigational Dermatology · 2019
    4. Hair Regrowth Outcomes of Contact Immunotherapy for Patients With Alopecia Areata JAMA Dermatology · 2018
    5. Topical 2% Tofacitinib for Children with Alopecia Areata, Alopecia Totalis, and Alopecia Universalis Journal of the American Academy of Dermatology · 2018
    6. Alopecia Areata: Treatment Options and Efficacy Journal of the American Academy of Dermatology · 2017
    7. Alopecia Areata: A Comprehensive Review of Pathogenesis and Management Clinical Reviews in Allergy & Immunology · 2017
    8. Methotrexate for the Treatment of Pediatric Alopecia Areata Journal of dermatological treatment · 2017
    9. Systematic Review and Quality Analysis of Studies on the Efficacy of Topical Diphenylcyclopropenone Treatment for Alopecia Areata Journal of The American Academy of Dermatology · 2017
    10. Higher Concentrations of Dithranol Appear to Induce Hair Growth Even in Severe Alopecia Areata Dermatologic therapy · 2017
    11. Bilateral Half-Head Comparison of 1% Anthralin Ointment in Children with Alopecia Areata Pediatric dermatology · 2017
    12. A Systematic Review of Pulse Steroid Therapy for Alopecia Areata Journal of the American Academy of Dermatology · 2016
    13. Comparison of Systemic Mycophenolate Mofetil with Topical Clobetasol in Lichen Planopilaris: A Parallel-Group, Assessor- and Analyst-Blinded, Randomized Controlled Trial American journal of clinical dermatology · 2015
    14. Efficacy and Safety of Diphenylcyclopropenone Alone or in Combination with Anthralin in the Treatment of Chronic Extensive Alopecia Areata: A Retrospective Case Series Journal of the American Academy of Dermatology · 2015
    15. Effectiveness of 308-nm Excimer Laser Therapy in Treating Alopecia Areata by Examining Treated Sides of Selected Alopecic Patches Dermatology · 2015
    16. Clobetasol Propionate, 0.05%, vs Hydrocortisone, 1%, for Alopecia Areata in Children JAMA dermatology · 2013
    17. The Safety and Efficacy of Diphencyprone for the Treatment of Alopecia Areata in Children Archives of dermatology · 2012
    18. Efficacy and Tolerability of Methotrexate in Severe Childhood Alopecia Areata British journal of dermatology/British journal of dermatology, Supplement · 2011
    19. Alopecia Areata Update Journal of The American Academy of Dermatology · 2010
    20. 308-nm Excimer Laser for the Treatment of Alopecia Areata in Children Pediatric dermatology · 2009
    21. Alopecia Areata: Review and Update Anais Brasileiros de Dermatologia · 2005
    22. Expression of Vascular Endothelial Growth Factor, Apoptosis Inhibitors (Survivin and p16) and CCL27 in Alopecia Areata Before and After Diphencyprone Treatment: An Immunohistochemical Study British Journal of Dermatology · 2004
    23. Chronic Delayed-Type Hypersensitivity Reaction as a Means to Treat Alopecia Areata Clinical & Experimental Immunology · 2004

    Related research 1

    1. Photochemotherapy and Alopecia Areata International Journal of Dermatology · 1983