Platelet-Rich Plasma: Molecular Mechanisms, Actions, and Clinical Applications in the Human Body

    November 2025 in “ International Journal of Molecular Sciences ”
    Wen-Shan Wu, Li-Ru Chen, Kuo-Hu Chen
    Studysummary This review covers the diverse clinical applications of platelet-rich plasma in regenerative medicine but provides no new clinical results.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
    Read the full study on mdpi.com →
    Discuss this study in the Community →

    Research cited in this study 17

    1. Impact of Age on Response to Platelet-Rich Plasma Therapy Skin Appendage Disorders · 2025
    2. Evaluating the Accuracy of Patient-Reported Hair Outcomes Versus Trichometric Measurements in PRP Therapy Archives of Dermatological Research · 2025
    3. A Comprehensive Review of Platelet-Rich Plasma for the Treatment of Dermatologic Disorders Journal of Dermatological Treatment · 2022
    4. Reversible Hair Loss in Lichen Planopilaris: Regrowth With Low-Dose Naltrexone and Platelet-Rich Plasma Journal of Drugs in Dermatology · 2022
    5. Platelet-Rich Plasma: New Performance Understandings and Therapeutic Considerations in 2020 Preprints.org · 2020
    6. Heterogeneity in Amount of Growth Factors Secreted by Platelets in Platelet-Rich Plasma Samples from Alopecia Patients Experimental dermatology · 2020
    7. Evaluation of Platelet-Rich Plasma as a Treatment for Androgenetic Alopecia: A Randomized Controlled Trial Journal of The American Academy of Dermatology · 2020
    8. The Utility of Platelet-Rich Plasma for the Treatment of Alopecia Journal of Drugs in Dermatology · 2020
    9. Systematic Review of Platelet-Rich Plasma Use in Androgenetic Alopecia Compared with Minoxidil, Finasteride, and Adult Stem Cell-Based Therapy International Journal of Molecular Sciences · 2020
    10. Growth Factor Concentrations in Platelet-Rich Plasma for Androgenetic Alopecia: An Intra-Subject, Randomized, Blinded, Placebo-Controlled, Pilot Study Experimental Dermatology · 2020
    11. Platelet-Rich Plasma for Facial Rejuvenation: An Early Examination Clinics in dermatology · 2019
    12. Evaluation of Non-Activated and Activated PRP in Hair Loss Treatment: Role of Growth Factor and Cytokine Concentrations Obtained by Different Collection Systems International Journal of Molecular Sciences · 2017
    13. Fibroblast Growth Factors Stimulate Hair Growth Through Beta-Catenin and Shh Expression in C57BL/6 Mice BioMed Research International · 2015
    14. Platelet-Rich Plasma as a Potential Treatment for Noncicatricial Alopecias International Journal of Trichology · 2015
    15. Platelet-Rich Plasma in Dermatology: Boon or Bane? Indian Journal of Dermatology, Venereology and Leprology · 2014
    16. Study of Platelet-Rich Plasma Injections in the Treatment of Androgenetic Alopecia Through a One-Year Period Journal of Cutaneous and Aesthetic Surgery · 2014
    17. Effects of Epidermal Growth Factor on the Morphology and Patterns of DNA Synthesis in Isolated Human Hair Follicles ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 1994