Methods and Models for the Investigation of the Uptake of Nanoparticles into Hair Follicles

    January 2014 in “ SciDok (Saarland University and State Library) ”
    Raber, Anne Susanne
    Studysummary This study demonstrated that in vitro pig ear models effectively predict human follicular uptake of nanoparticles for potential transfollicular vaccination, but massage did not enhance nanoparticle penetration.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
    Read the full study on publikationen.sulb.uni-saarland.de →
    Discuss this study in the Community →

    Research cited in this study 17

    1. Quantification of Nanoparticle Uptake Into Hair Follicles in Pig Ear and Human Forearm Journal of Controlled Release · 2014
    2. Iontophoresis-Targeted, Follicular Delivery of Minoxidil Sulfate for the Treatment of Alopecia Journal of Pharmaceutical Sciences · 2013
    3. Pattern Hair Loss in Men: Diagnosis, Genetic Link, Clinical Features, and Treatments Dermatologic Clinics · 2012
    4. Selective Follicular Targeting by Modification of the Particle Sizes Journal of Controlled Release · 2011
    5. The Extent of the Uptake of Plasmid Into the Skin Determines the Immune Responses Induced by a DNA Vaccine Applied Topically Onto the Skin Journal of Pharmacy and Pharmacology · 2011
    6. Nanoparticle-Based Targeting of Vaccine Compounds to Skin Antigen-Presenting Cells by Hair Follicles and Their Transport in Mice ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2008
    7. Comparison of Artificial Sebum with Human and Hamster Sebum Samples International journal of pharmaceutics · 2008
    8. In Vitro Permeation of Drugs Into Porcine Hair Follicles: Is It Quantitatively Equivalent to Permeation Into Human Hair Follicles? Journal of Pharmacy and Pharmacology · 2008
    9. The Role of Hair Follicles in the Percutaneous Absorption of Caffeine BJCP. British journal of clinical pharmacology/British journal of clinical pharmacology · 2007
    10. Immunization by Application of DNA Vaccine onto a Skin Area Where the Hair Follicles Have Been Induced into Anagen-Onset Stage Molecular therapy · 2007
    11. Transfollicular Drug Delivery: Is It a Reality? International journal of pharmaceutics · 2005
    12. Differential Stripping: Determination of the Amount of Topically Applied Substances Penetrated into the Hair Follicles ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2005
    13. Penetration Profile of Microspheres in Follicular Targeting of Terminal Hair Follicles ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2004
    14. Variations of Hair Follicle Size and Distribution in Different Body Sites Journal of Investigative Dermatology · 2004
    15. Efficient Delivery of Transgenes to Human Hair Follicle Progenitor Cells Using Topical Lipoplex Nature biotechnology · 2000
    16. The Human Hair Follicle: A Reservoir of CD40+ B7-Deficient Langerhans Cells That Repopulate Epidermis After UVB Exposure ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 1998
    17. Description of the Intrafollicular Delivery of Large Molecular Weight Molecules to Follicles of Human Scalp Skin In Vitro Journal of Pharmaceutical Sciences · 1997

    Related research 4

    1. Unlocking the Vital Role of Host Cells in Hair Follicle Reconstruction by Semi-Permeable Capsules PLOS ONE · 2017
    2. Drug Delivery to Hair Follicles Expert opinion on drug delivery · 2013
    3. Hair Follicle Targeting with Nanoparticles Springer eBooks · 2012
    4. Investigation of the Penetration and Storage of a Shampoo Formulation Containing Caffeine into the Hair Follicles by In Vivo Laser Scanning Microscopy Laser Physics Letters · 2007