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This study demonstrated that minoxidil-encapsulated PLLGA nanoparticles significantly increased minoxidil delivery to hair follicles compared to a minoxidil aqueous solution in mice.

This study investigated the use of Minoxidil encapsulated in HA-PLGA nanoparticles for alopecia treatment and found that these nanoparticles efficiently delivered the drug to hair follicle cells without significant cytotoxicity, offering a potential transdermal delivery method for various diseases.

This study demonstrated that in vitro pig ear models effectively predict human follicular uptake of nanoparticles for potential transfollicular vaccination, but massage did not enhance nanoparticle penetration.

Phospholipid-coated nanoparticles penetrate hair follicles better than others, especially in pig ears.

This study demonstrated that using PLGA nanoparticles to deliver chlorogenic acid significantly increased type 17 collagen production in human epidermal cells, indicating potential for improved skincare formulations.