More Than One Gene Involved in Monilethrix: Intracellular but Also Extracellular Players

    May 2006 in “ Journal of Investigative Dermatology ”
    Jürgen Schweizer
    Studysummary Monilethrix involves multiple genes affecting hair structure, including DSG4 mutations.
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    Research cited in this study 12

    1. An Autosomal Recessive Form of Monilethrix Is Caused by Mutations in DSG4: Clinical Overlap with Localized Autosomal Recessive Hypotrichosis Journal of Investigative Dermatology · 2006
    2. Mutations in the Desmoglein 4 Gene Underlie Localized Autosomal Recessive Hypotrichosis with Monilethrix Hairs and Congenital Scalp Erosions Journal of Investigative Dermatology · 2006
    3. Mutations in the Desmoglein 4 Gene Are Associated with Monilethrix-Like Congenital Hypotrichosis ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2006
    4. A Missense Mutation in the Cadherin Interaction Site of the Desmoglein 4 Gene Underlies Localized Autosomal Recessive Hypotrichosis Journal of Investigative Dermatology · 2005
    5. A Missense Mutation in the Type II Hair Keratin hHb3 Is Associated with Monilethrix Journal of Medical Genetics · 2005
    6. Keratins of the Human Hair Follicle International review of cytology · 2005
    7. Intragenic Deletion in the Desmoglein 4 Gene Underlies the Skin Phenotype in the Iffa Credo Hairless Rat Differentiation · 2004
    8. A Recurrent Intragenic Deletion in the Desmoglein 4 Gene Underlies Localized Autosomal Recessive Hypotrichosis Journal of Investigative Dermatology · 2004
    9. The Lanceolate Hair Rat Phenotype Results from a Missense Mutation in a Calcium Coordinating Site of the Desmoglein 4 Gene Genomics · 2004
    10. Lanceolate Hair-J (LahJ): A Mouse Model for Human Hair Disorders Experimental dermatology · 2000
    11. Evidence for Genetic Heterogeneity in Monilethrix Journal of Investigative Dermatology · 1996
    12. Lanceolate Hair (Lah): A Recessive Mouse Mutation with Alopecia and Abnormal Hair ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 1996

    Related research 1

    1. Histopathology of Hypotrichosis with Juvenile Macular Dystrophy The American Journal of Dermatopathology · 2004