New Insights Into MicroRNA in Dermatological Diseases

    August 2025 in “ Frontiers in Medicine
    Mengting Xu, Jiadong Yan, Xin Wang, Yue Zhang, Shengju Yang
    TLDR MicroRNAs could lead to new treatments for skin diseases, but more research is needed.
    MicroRNAs (miRs) are non-coding RNA molecules that play a crucial role in regulating gene expression and are involved in various physiological processes. They are being explored as biomarkers and therapeutic targets for dermatological diseases such as psoriasis, skin wounds, systemic sclerosis, skin tumors, and systemic lupus erythematosus. MiRs influence skin pathophysiology through mechanisms like oxidative stress, inflammation, apoptosis, and angiogenesis. Understanding miRs and their regulatory targets is vital for advancing skin disease treatment. While miRs combined with new materials may offer innovative therapies, more research is needed to translate these findings into clinical applications.
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