Alterations in Methionine Cycle and Wnt/MAPK Signaling Associated with HMBi-Induced Cashmere Growth in Goats

    February 2025 in “ International Journal of Molecular Sciences ”
    Minjie Xi, Jiali Jiang, Wei Wang … Ruiyang Zhang
    Studysummary This study found that supplementing Liaoning cashmere goats with HMBi increased cashmere length while decreasing its diameter, attributed to changes in Met-related metabolites and elevated expression of genes related to the Met cycle and cell differentiation pathways such as Wnt and MAPK.
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    Research cited in this study 8

    1. Methionine Can Mitigate Hair Follicle Development Bias in Heat-Stressed Rex Rabbits The FASEB Journal · 2022
    2. Defining MicroRNA Signatures of Hair Follicular Stem and Progenitor Cells in Healthy and Androgenic Alopecia Patients Journal of Dermatological Science · 2020
    3. Discovery of Differentially Expressed Genes in Cashmere Goat Hair Follicles by RNA Sequencing Genetics and Molecular Research · 2016
    4. Immunohistochemical Study of Hair Follicle Stem Cells in Regenerated Hair Follicles Induced by Wnt10b International Journal of Medical Sciences · 2016
    5. Regulatory Effect of Beta-Catenin on Proliferation of Hair Follicle Stem Cells Involves PI3K/Akt Pathway Journal of Applied Biomedicine · 2013
    6. Defining BMP Functions in the Hair Follicle by Conditional Ablation of BMP Receptor IA The Journal of Cell Biology · 2003
    7. Control of Hair Growth and Follicle Size by VEGF-Mediated Angiogenesis Journal of Clinical Investigation · 2001
    8. Protein And Sulfur Amino Acid Nutrition Of Hair Fiber-Producing Angora And Cashmere Goats Livestock production science · 2000

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