Melatonin as an Antioxidant and Immunomodulator in Atopic Dermatitis–A New Look on an Old Story–A Review

    June 2021 in “ Preprints.org ”
    Andrzej Jaworek, Jacek C. Szepietowski, Przemysław Hałubiec, Anna Wojas‐Pelc, Jolanta Jaworek
    TLDR Melatonin may help with atopic dermatitis by reducing inflammation and improving sleep.
    This review explored the role of melatonin (MT) in atopic dermatitis (AD), highlighting its potential as an antioxidant and immunomodulator. AD is a chronic inflammatory skin condition that often disrupts sleep, impacting patients' quality of life. Melatonin, known for regulating sleep/wake cycles, was examined for its antioxidant and anti-inflammatory properties, which could connect skin inflammation and sleep issues in AD. The review aimed to summarize experimental and clinical studies on MT's effects in AD, suggesting its potential as a biomarker for disease severity and a target for new therapies.
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