29 citations
,
April 2004 in “Annals of Pharmacotherapy” This review concluded that finasteride may reduce hirsutism scores and hair diameter in women with hyperandrogenism, but concerns about teratogenicity and long-term safety make it a secondary treatment option.
47 citations
,
March 2004 in “European journal of endocrinology” This study found that the combination of spironolactone and finasteride significantly improved hirsutism scores more than spironolactone alone in women, with similar side-effect profiles between treatments.
20 citations
,
December 2003 in “Journal of Cosmetic and Laser Therapy” This study found that an 800-nm diode laser was effective for reducing pigmented hair and extending hair plucking intervals, with most patients tolerating the procedure well without anesthetics.
192 citations
,
September 2003 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism” This study suggests that metformin may be more effective than Dianette in treating moderate to severe hirsutism in women with PCOS, while also reducing markers of insulin resistance.
195 citations
,
May 2003 in “Obstetrics and gynecology (New York. 1953. Online)/Obstetrics and gynecology” This review discusses the diagnosis and treatment of hirsutism, emphasizing that a systematic evaluation can determine its cause, while combination therapy effectively manages the condition for most patients.
125 citations
,
February 2003 in “Journal of the American Academy of Dermatology” This review discusses various forms and categories of hypertrichosis, as well as methods for managing the condition, but does not report new clinical results.
27 citations
,
January 2001 in “Hormone Research in Paediatrics” This study found that a lower maintenance dose of flutamide (125 mg/day) effectively maintained the reduction in hirsutism achieved with an initial higher dose (250 mg/day) in women, without additional side effects.
115 citations
,
January 2001 in “American journal of clinical dermatology” This study found that eflornithine 15% cream reduced unwanted facial hair growth more effectively than a placebo in women with hirsutism, but hair growth returned to pretreatment levels within 8 weeks of stopping treatment.
46 citations
,
December 2000 in “Seminars in Cutaneous Medicine and Surgery” This article discusses the use of lasers and light sources for hair removal and reports no new clinical results; it emphasizes the significance of selecting the appropriate laser system and treatment protocol for effective and safe outcomes.
67 citations
,
January 1997 in “Lancet” This article discusses the causes of hirsutism, identifying increased androgen production and heightened skin sensitivity, and provides no new clinical results.
94 citations
,
July 1991 in “Clinical endocrinology” In this study, cyproterone acetate at 2 mg daily was found to be as effective as higher doses in reducing hair growth for hirsute women over 12 months.