115 citations
,
January 2001 in “American journal of clinical dermatology” This study found that eflornithine 15% cream reduced unwanted facial hair growth more effectively than a placebo in women with hirsutism, but hair growth returned to pretreatment levels within 8 weeks of stopping treatment.
50 citations
,
May 2000 in “Fertility and Sterility” This study found that flutamide was more effective than finasteride in reducing hair growth in women with hirsutism over a one-year period.
46 citations
,
January 2000 in “The Journal of Clinical Endocrinology and Metabolism”
27 citations
,
November 1998 in “Journal of Endocrinological Investigation” This study reported that 6 months of finasteride treatment significantly improved idiopathic hirsutism in women, with benefits persisting 6 months post-treatment and no adverse reactions observed.
52 citations
,
June 1998 in “British journal of dermatology/British journal of dermatology, Supplement” This study found that normal mode ruby laser treatment for hirsutism is well tolerated and results in significant hair count reduction for at least six months, with multiple treatments offering greater effects.
76 citations
,
December 1997 in “Fertility and Sterility” This study found that spironolactone was significantly more effective than finasteride in reducing hirsutism scores over 9 months, despite more side effects occurring in the spironolactone group.
67 citations
,
October 1997 in “Dermatologic Surgery” This study found that the EpiLight Hair Removal System achieved approximately 60% hair removal after 12 weeks following a single treatment, indicating effectiveness and safety for long-term hair reduction.
30 citations
,
April 1997 in “European journal of endocrinology” The document concludes that managing hirsutism involves identifying the cause, using a scoring system for severity, combining cosmetic and medical treatments, encouraging weight loss, and providing psychological support, while noting the need for more research on drug treatments.
132 citations
,
October 1995 in “Journal of the American Academy of Dermatology” This report concludes that the blend method is the most effective electrolysis technique for permanent hair removal, requiring proper technique and preparation such as shaving before treatment to increase efficacy.
31 citations
,
January 1995 in “The American journal of medicine” This article reviews the role of 5α-reductase in cutaneous hyperandrogenism and the potential of 5α-reductase inhibitors and antiandrogens in treating conditions like hirsutism and male-pattern baldness, reporting no clinical results.
34 citations
,
January 1995 in “The Journal of Clinical Endocrinology and Metabolism” 43 citations
,
December 1993 in “Annals of internal medicine” This letter discusses the first reported case of serious liver damage linked to the use of flutamide for hirsutism in a woman, highlighting a potential risk for hepatotoxicity with this treatment.
89 citations
,
March 1990 in “PubMed” This study found that shaving was the most helpful and commonly used temporary hair removal method among women with facial hirsutism.
78 citations
,
May 1989 in “The Journal of Clinical Endocrinology & Metabolism” This study found that in hirsute women, daily treatment with 200 mg spironolactone significantly reduced hair growth rates and hair shaft diameters on various body areas over 12 months.
58 citations
,
March 1985 in “Journal of The American Academy of Dermatology” This review discusses the historical, legal, and clinical aspects of electrolysis and thermolysis, highlighting potential risks due to the lack of standardized training for electrologists in the United States, but reports no new clinical results.
124 citations
,
September 1980 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism” This study found that spironolactone significantly reduced hair growth in hirsute women, with noticeable effects in 3-5 months, and decreased serum testosterone levels in all participants.
37 citations
,
January 1975 in “Journal of Experimental Zoology” This study found that thyroxine increased hair growth rate in rats, but estradiol decreased it, with both hormones affecting follicular cycles independently without altering ultimate hair length.