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In this study, hair bleaching with ammonium persulfate and hydrogen peroxide caused significant damage to hair structure and severe skin reactions in rats, highlighting the need for cautious bleaching procedures.

In this study, researchers observed that cosmetic peroxide bleaching causes oxidative damage and protein loss in human hair, not only affecting the cuticle but also deeper cortical structures, correlating with bleaching severity.

This case report indicates that contact dermatitis on the face can result from using a bleaching ointment containing ammonium bisulfite during hair-dyeing.

This study observed that bleaching brown human hair with persulfate salts and hydrogen peroxide induced significant conformational changes in keratin, particularly affecting disulfide bridges and oxidized sulfur species, which may inform the development of hair restorative treatments.

This study found that bleaching significantly damages hair structure and increases combing difficulty, while dyeing with emulsifiers can partially reduce damage and improve combability, yet both processes cause notable protein loss.