Characterization of Factors That Determine Lentiviral Vector Tropism in Skin Tissue Using an Ex Vivo Model

    March 2011 in “ The Journal of Gene Medicine ”
    Nikolai Kunicher, Tomer Tzur, Dalit Amar … Amos Panet
    Studysummary This study found that lentiviral vector tropism in three-dimensional skin tissue is distinct from keratinocytes in culture and is influenced by complex extracellular interactions.
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    Research cited in this study 9

    1. Differential Expression of Stem Cell Markers in Human Follicular Bulge and Interfollicular Epidermal Compartments Histochemistry and Cell Biology · 2010
    2. Lentiviral Vector-Mediated Gene Transfer to Human Hair Follicles Journal of Investigative Dermatology · 2009
    3. Epidermal Homeostasis: A Balancing Act of Stem Cells in the Skin Nature Reviews Molecular Cell Biology · 2009
    4. Expression of the Hair Stem Cell-Specific Marker Nestin in Epidermal and Follicular Tumors PubMed · 2008
    5. Epithelial Stem Cells: Turning Over New Leaves Cell · 2007
    6. Stem Cells and Their Niches Science · 2006
    7. Keratin 15 Promoter Targets Putative Epithelial Stem Cells in the Hair Follicle Bulge Journal of Investigative Dermatology · 2003
    8. Morphogenesis and Renewal of Hair Follicles from Adult Multipotent Stem Cells Cell · 2001
    9. Involvement of Follicular Stem Cells in Forming Not Only the Follicle but Also the Epidermis Cell · 2000