Keratin 14 in Skin and Hair Follicle of Rats During Postnatal Development Period

January 2001 in “ Acta Academiae Medicine Militaris Tertiae ”

Zeng Yi

keratin 14 K14 mRNA hair cycle hair follicles keratinizing epidermal cells stratum basal stratum spinosum sebaceous gland cells

Studysummary In this study, the researchers reported that the expression of keratin 14 in the skin and hair follicles of neonatal and juvenile rats differs from that observed in adults or human embryos. Our plain-language summary of this paper — not a Tressless recommendation.

The study investigated the hair cycle and keratin 14 mRNA (K14 mRNA) distribution in the skin and hair follicles of 69 neonatal and postnatal Wistar rats. It was found that the first hair cycle was significantly shorter than the second. K14 expression was primarily localized in the keratinizing epidermal cells of the stratum basal/spinosum, hair follicles, and some sebaceous gland cells, with no positive signals in other cell types or regions. The study concluded that K14 expression in newborn and juvenile rats differed from that in adults or human embryos.

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