TLDR Hair follicles in C57BL/6 mice develop rapidly from late embryonic stages to shortly after birth, with key growth and regeneration phases identified.
The study investigated the development of hair follicles in C57BL/6 mice at various life stages. It was found that hair follicle development began at embryonic day 15.5 (E15.5) and the number of hair follicles increased rapidly from E17.5 to 3 days after birth. By the 9th day after birth, most hair follicles reached the 8th stage of development. In adult mice, 95% of hair follicles entered the growth stage IV after depilation, with a significant portion entering the degradation period by day 22. This period of rapid hair follicle increase was suggested as a key phase for studying hair follicle regeneration mechanisms.
5 citations
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November 2015 in “International Journal of Radiation Biology” Gamma-ray exposure can cause long-lasting damage to hair follicles, affecting hair structure and color.
10 citations
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January 2014 in “Genetics and Molecular Research” Liaoning Cashmere goat hair follicles show synchronized growth patterns with lowest activity in May.
September 2013 in “中国医师杂志” Human scalp hair follicles grow well in Williams E medium, which may help with hair transplants.
5 citations
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January 2013 in “Cells Tissues Organs” Activin B helps start and grow hair follicles in mice.
Injecting follicular cells into skin can lead to the formation of new hair follicles.
January 2008 in “Anhui nongye kexue” Mongolia sheep hair follicles grew well in a serum-free medium for 19 days.
27 citations
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November 2005 in “Archives of Dermatological Research” Choosing hair follicles at the same growth stage leads to more consistent hair growth experiments.
January 2003 in “Journal of the Fourth Military Medical University” Hair follicles can regenerate if cut at certain points, with stem cells in the upper part.
