The Experimental Study of C57BL/6 Mouse Skin Hair Follicle Development

    January 2010 in “ Chinese journal of clinical anatomy ”
    Lin Zhang
    TLDR Hair follicles in C57BL/6 mice develop rapidly from late embryonic stages to shortly after birth, with key growth and regeneration phases identified.
    The study investigated the development of hair follicles in C57BL/6 mice at various life stages. It was found that hair follicle development began at embryonic day 15.5 (E15.5) and the number of hair follicles increased rapidly from E17.5 to 3 days after birth. By the 9th day after birth, most hair follicles reached the 8th stage of development. In adult mice, 95% of hair follicles entered the growth stage IV after depilation, with a significant portion entering the degradation period by day 22. This period of rapid hair follicle increase was suggested as a key phase for studying hair follicle regeneration mechanisms.
    Discuss this study in the Community →

    Related Community Posts Join

    6 / 1000+ results

      community Keratin microspheres - breakthrough

      in Research/Science  13 upvotes 9 months ago
      A gel of keratin microspheres promotes hair follicle growth, showing similar effectiveness to minoxidil in mice. The treatment activates hair growth pathways and reduces inflammation, with potential applications in drug delivery for hair-related disorders.

      community Anyone Try Microneedling with Exosomes/AAPE?

      in Microneedling  2 upvotes 2 years ago
      User asks where to purchase exosomes/AAPE for microneedling hair loss treatment. Links to research on hair regeneration therapy, stem cell therapy, exosome therapy, and dermal exosomes provided.

      community (Serious) Updates and discussion, new treatments in development

      in Treatment  7 upvotes 5 months ago
      Finasteride, minoxidil, and derma rolling are currently the best treatments for hair loss. New treatments like TDM-105795, GT20029, PP405, HMI 115, Tsuji, Scube 3, RU, JW0061, Topilutamide, and verteporfin show promise but have uncertain timelines.

    Related Research

    7 / 7 results