In Vitro Culture and Histological Characterization of Extracted Human Hair Follicles

January 2013 in “ Journal of Clinical & Experimental Dermatology Research ”

Rattapon Thuangtong

hair follicles in vitro culture catagen stage outer root sheath cells apoptosis hair follicle biology drug delivery targets

TLDR Human hair follicles can be grown in a lab for about a week.

This study demonstrated that human hair follicles could be successfully cultured in vitro for at least 7 days before entering the catagen stage, characterized by upward regression and apoptosis of outer root sheath cells. The follicles initially grew at a rate of approximately 200 μm/day for the first four days, with growth ceasing after an average of 8.4 days. This in vitro model provided valuable insights into hair follicle biology and potential drug delivery targets.

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