Human Hair Follicle and Interfollicular Keratinocyte Reactivity to Mouse HPV16-Transformed Cells: An In Vitro Study

    July 2008 in “ Oncology Reports ”
    Karel Smetana, Barbora Dvořánková, Lukáš Lacina … Vladimı́r Vonka
    Studysummary In this study, TC-1 cells, resembling stromal cells formed by epithelial-mesenchymal transition, significantly affected the behavior of normal human keratinocytes, supporting the role of stromal cells in tumor progression.
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    Research cited in this study 6

    1. Porcine Epidermal Stem Cells as a Biomedical Model for Wound Healing and Normal/Malignant Epithelial Cell Propagation Theriogenology · 2006
    2. Transient Expression of Keratin 19 Induced by Adhesion in Originally Negative Interfollicular Epidermal Cells PubMed · 2005
    3. New Aspects of Galectin Functionality in Nuclei of Cultured Bone Marrow Stromal and Epidermal Cells: Biotinylated Galectins as a Tool to Detect Specific Binding Sites Biology of the Cell · 2003
    4. Molecular Mechanisms Regulating Hair Follicle Development ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2002
    5. Regulation of Keratin 9 in Nonpalmoplantar Keratinocytes by Palmoplantar Fibroblasts Through Epithelial-Mesenchymal Interactions ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 1999
    6. Keratin 19 as a Biochemical Marker of Skin Stem Cells In Vivo and In Vitro: Localization and Variation with Age and Culture Stage Journal of Cell Science · 1996