Development of Hair Keratin Protein to Accelerate Oral Mucosal Regeneration

The study "Development of Hair Keratin Protein to Accelerate Oral Mucosal Regeneration" involved the extraction and PEGylation of human hair keratin proteins, which were then tested on normal human oral keratinocytes (HOKs) and human gingival fibroblasts (HGFs). The keratin was found to be non-toxic to these cells. An in vitro migration assay was conducted to assess the impact of the keratin on cell movement, with the degree of movement assessed after 12 and 24 hours of incubation. The study also involved immunofluorescence staining to observe the cells' response to the keratin. The results were statistically analyzed, with the mean±standard error obtained from at least three independent experiments. The study suggests that hair keratin protein could potentially be used to accelerate oral mucosal regeneration, although further research is needed to confirm these findings.