Factors Influencing Hair Growth in Physiology

June 2005

류은주

epithelial cells mesenchymal cells hair follicles epidermal growth factor transforming growth factor insulin-dependent growth factor hepatocyte growth factor arachidonic acid eicosanoid hormones androgen testosterone hair keratin-producing cells EGF TGF IGF-I HGF

TLDR Hair growth is controlled by cell interactions and influenced by specific growth factors and hormones.

The study found that hair growth was regulated by interactions between epithelial and mesenchymal cells in hair follicles. Epidermal growth factor (EGF) and transforming growth factor (TGF) had controlling effects on hair growth, while insulin-dependent growth factor (IGF-I) and hepatocyte growth factor (HGF) acted as stimulators. IGF-I influenced blood sugar levels and the production of arachidonic acid, an essential fatty acid. Additionally, eicosanoid hormones, derived from male hormones like androgen and testosterone, controlled hair keratin-producing cells, correlating with arachidonic acid production.

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