Search

for
Search:

Glossary Transforming Growth Factor

proteins regulating cell growth, differentiation, and immune responses

Transforming Growth Factor (TGF) refers to a group of proteins that play crucial roles in regulating cell growth, differentiation, and immune responses. There are two main types, TGF-α and TGF-β, with TGF-β being particularly important in processes like wound healing, fibrosis, and the regulation of the immune system. These factors are significant in both normal physiological processes and in the development of diseases such as cancer and fibrosis.

Related Terms

Research

5 / 1000+ results

Transforming Growth Factor-Beta in Stem Cells and Tissue Homeostasis

research Transforming growth factor-β in stem cells and tissue homeostasis

245 citations , January 2018 in “Bone Research”

This review discusses the role of TGF-β signaling in stem cell recruitment and tissue regeneration, indicating that abnormalities in TGF-β activation contribute to various major diseases and suggesting avenues for therapeutic intervention.

Differential Expression of Fibromodulin, a Transforming Growth Factor-Beta Modulator, in Fetal Skin Development and Scarless Repair

research Differential Expression of Fibromodulin, a Transforming Growth Factor-β Modulator, in Fetal Skin Development and Scarless Repair

168 citations , August 2000 in “American Journal of Pathology”

This study suggests that fibromodulin may regulate transforming growth factor-β activity during scar formation, influencing the transition from fetal scarless repair to adult scar-forming repair in rats.

research Transforming Growth Factor-β Receptor Type I and Type II Expression During Murine Hair Follicle Development and Cycling

148 citations , October 1997 in “Journal of Investigative Dermatology”

TGF-β receptors are crucial for hair follicle development.

Ontogenetic Transition in Fetal Wound Transforming Growth Factor-Beta Regulation Correlates with Collagen Organization

research Ontogenetic Transition in Fetal Wound Transforming Growth Factor-β Regulation Correlates with Collagen Organization

109 citations , December 2003 in “American Journal of Pathology”

This study observed that the ontogenetic transition from scarless repair in early fetal rat wounds to scar-forming repair in late gestation is associated with differential TGF-β ligand and receptor expression patterns.

research Age-Related Loss of Innate Immune Antimicrobial Function of Dermal Fat Is Mediated by Transforming Growth Factor Beta

96 citations , December 2018 in “Immunity”

This study found that inhibiting TGF-β receptors in adult dermal fibroblasts restored their function and increased resistance to Staphylococcus aureus infection by enhancing their adipogenic and antimicrobial capabilities.

View more "transforming growth factor" in research →

Community Join

5 / 37 results

community A Theory on Why Microneedling Works

175 upvotes 6 years ago

Microneedling may enhance hair regrowth by transferring stem cells to dormant follicles, improving the effects of minoxidil. Users discuss using microneedling with needle lengths around 1.5mm to stimulate hair growth.

community Taurine supplements work for hair growth?

9 upvotes 2 years ago

The conversation discusses taurine supplements for hair growth, highlighting their potential to reduce DHT and improve hair health. A user comments that people often try alternatives to finasteride.

community PP405: The Ultimate Hair Loss Drug for Complete Hair Growth

211 upvotes 1 year ago

PP405 is a new hair loss treatment in phase 2 trials that may promote hair growth by increasing lactate production and activating hair follicle stem cells. It could potentially replace hormone-disrupting treatments like Minoxidil and finasteride.

community The Real Cause Of Androgenetic Alopecia

675 upvotes 1 year ago

Androgenetic alopecia is caused by DHT affecting hair growth. Finasteride and minoxidil are used to manage hair loss by blocking DHT and promoting hair growth.

community Amplifica: Hope or Cope? A Review of Their Pipeline

9 upvotes 1 month ago

Amplifica's AMP-303 showed a modest increase in hair growth, but results were inconsistent and potentially misleading. Hyaluronic acid and osteopontin are being explored for hair growth, with varying effects on different hair types and conditions.

View more "transforming growth factor" in community →

Learn

6 / 801 results

learn Exosomes

Microscopic delivery system that sends growth-promoting signals to hair follicles

learn Epidermal Growth Factor

learn Follistatin

glycoprotein that inhibits TGF-β and promotes hair growth by antagonizing activin

learn Vascular Endothelial Growth Factor

learn Stem Cell Factor

learn Platelet-Rich Plasma

What is Platelet-Derived Growth Factor Beta Polypeptide, and how does it help stimulate new hair growth? PDGF-BB is a growth factor that signals to dermal papilla cells and promotes blood-vessel formation; mouse studies report it can push follicles into the growth phase, and human evidence comes only indirectly from PRP trials. No PDGF product is approved for hair restoration and there is no published human trial of PDGF-BB on its own.

View more "transforming growth factor" in learn →

Clinics

6 / 17 results

All 17 clinic results →

Experts

— no results

Try a deeper search in experts →