Defects in Mitochondrial DNA Replication and Oxidative Damage in Muscle of mtDNA Mutator Mice
October 2014
in “
Free radical biology & medicine
”
alopecia graying of hair oxidative damage mitochondrial dysfunction mitochondrial DNA replication oxidative modifications antioxidants mitochondrial biogenesis DNA repair enzymes hair loss gray hair oxidative stress mitochondrial issues DNA replication oxidative changes antioxidant levels mitochondrial growth DNA repair
Studysummary This study found that oxidative damage is present in the mitochondria of PolG mice, which exhibit premature aging-like phenotypes due to mitochondrial dysfunction.
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