Refractory Alopecia Areata of the Beard: Novel Improvement Through Exosome Therapy With Signs of Hair Repigmentation

    December 2025 in “ Clinical Case Reports
    Asem Shadid, Khalid Nabil Nagshabandi, Abdullah Al‐Omair
    TLDR Exosome therapy helped regrow and repigment beard hair in a man with alopecia.
    Exosome therapy has demonstrated promising results in treating a 35-year-old male patient with refractory alopecia areata of the beard, who had not responded to traditional treatments. After two sessions of exosome injections, significant hair regrowth, repigmentation of white hairs to black, and scar improvement were observed. This case highlights the potential of exosome therapy as a minimally invasive and effective treatment for alopecia areata, particularly in cases unresponsive to conventional therapies. The study suggests that exosome therapy could become a valuable option in regenerative medicine for dermatological conditions, though further research with larger sample sizes is needed to confirm its long-term efficacy and safety.
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