Evaluation of androgen receptor gene as a candidate gene in female androgenetic alopecia

This study evaluated the androgen receptor (AR) gene as a candidate gene for female androgenetic alopecia (AGA) and found no significant difference in genotype or allele frequency between patients and controls. The study concluded that the AR gene is not a major contributing factor in the pathogenesis of female AGA and that female AGA should be considered a different disease from male AGA. The study suggests that other candidate genes affecting plasma and/or tissue androgen concentrations are required for phenotypic expression, and future genetic studies should be conducted on a larger scale with different types of female AGA.