Enhanced Skin Penetration of Finasteride Loaded DMSO-Liposomes for the Treatment of Androgenic Alopecia: Comparison with Conventional Liposomes

    January 2023 in “ Drug Development and Industrial Pharmacy ”
    Shweta Ramkar, Monika Kaurav, M S Sudheesh, Ravi Shankar Pandey
    Studysummary This study observed that DMSO-modified liposomes enhanced the topical delivery of finasteride, improving hair follicle density and growth phase ratio in a rat model of testosterone-induced alopecia.
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    Research cited in this study 10

    1. Co-Loading of Finasteride and Baicalin in Phospholipid Vesicles Tailored for the Treatment of Hair Disorders Nanoscale · 2020
    2. Exploring the Potential of Minoxidil Tretinoin Liposomal-Based Hydrogel for Topical Delivery in the Treatment of Androgenic Alopecia Cutaneous and Ocular Toxicology · 2019
    3. Melatonin Vitamin C-Based Nanovesicles for Treatment of Androgenic Alopecia: Design, Characterization and Clinical Appraisal European Journal of Pharmaceutical Sciences · 2018
    4. Quantification of Nanoparticle Uptake Into Hair Follicles in Pig Ear and Human Forearm Journal of Controlled Release · 2014
    5. Safety and Efficacy Analysis of Liposomal Insulin-Like Growth Factor-1 in a Fluid Gel Formulation for Hair-Loss Treatment in a Hamster Model Clinical and Experimental Dermatology · 2012
    6. Finasteride and Sexual Side Effects Indian Dermatology Online Journal · 2012
    7. Prevention and Treatment of Alopecia Areata with Quercetin in the C3H/HeJ Mouse Model Cell stress & chaperones · 2011
    8. Development of Liposomal Systems of Finasteride for Topical Applications: Design, Characterization, and In Vitro Evaluation Pharmaceutical Development and Technology · 2007
    9. Enhancement of Follicular Delivery of Finasteride by Liposomes and Niosomes International Journal of Pharmaceutics · 2006
    10. Percutaneous Absorption of a New Antiandrogen Included in Liposomes or in Solution International Journal of Pharmaceutics · 1995

    Related research 2

    1. Innovative Liposomes as a Transfollicular Drug Delivery System: Penetration into Porcine Hair Follicles Journal of Investigative Dermatology · 2006
    2. Study on Transdermal Permeation and Skin Accumulation of Finasteride Ethosomes Zhōnghuá yàoxué zázhì · 2004