Assessing the Efficacy and Quality of Life Improvements of Botulinum Toxin Type A With Topical Minoxidil Versus Topical Minoxidil in Male Androgenetic Alopecia: A Randomized Controlled Trial

    Linli Yu, SathishKumar Moorthy, Xutong Li, Lingli Peng, Zikai Zhang, Liangliang Shen, Yu Han, Xiaofeng Huang
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    TLDR Combining botulinum toxin type A with Minoxidil leads to better hair growth and quality of life in men with hair loss.
    The study investigated the efficacy and safety of combining botulinum toxin type A (BTA) with topical Minoxidil in treating male androgenetic alopecia (AGA). Involving 60 male patients, the treatment group received BTA injections along with 5% Minoxidil, while the control group received only 5% Minoxidil. Results showed significant hair growth and improved Investigator Global Assessment (IGA) scores in the treatment group at the 4th and 6th months compared to the control group. Additionally, patient satisfaction and quality of life improvements were higher in the treatment group, with no adverse reactions reported. The combination of BTA and Minoxidil was more effective than Minoxidil alone in promoting hair growth and enhancing quality of life in male AGA patients.
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