Assessing the Efficacy and Quality of Life Improvements of Botulinum Toxin Type A With Topical Minoxidil Versus Topical Minoxidil in Male Androgenetic Alopecia: A Randomized Controlled Trial

    Linli Yu, SathishKumar Moorthy, Xutong Li … Xiaofeng Huang

    Preprint — not peer reviewed. This was posted to a preprint server or data repository. It has not been through a journal's review process, and its findings may change or not hold up.

    Studysummary This study observed that combining botulinum toxin type A with Minoxidil significantly promoted hair growth, improved quality of life, and enhanced patient satisfaction in male androgenetic alopecia patients at 4 and 6 months, with no adverse effects compared to using Minoxidil alone.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
    Read the full study on researchsquare.com →
    Discuss this study in the Community →

    Research cited in this study 17

    1. Prospective Efficacy and Safety Study of an Innovative Kerascalp Hair Growth Serum in Mild-to-Moderate Alopecia in India: Regrowth Study Cureus · 2023
    2. Quality of Life and Its Association With Androgenetic Alopecia Patients in Shanghai: A Cross-Sectional Study Clinical, Cosmetic and Investigational Dermatology · 2022
    3. A Study of Combination Unilateral Subcutaneous Botulinum Toxin A Treatment for Androgenetic Alopecia Journal of Cosmetic Dermatology · 2022
    4. Treatment Options for Androgenetic Alopecia: Efficacy, Side Effects, Compliance, Financial Considerations, and Ethics Journal of Cosmetic Dermatology · 2021
    5. Is There a Rationale for the Use of Botulinum Toxin in the Treatment of Androgenetic Alopecia? Journal of Cosmetic Dermatology · 2021
    6. Androgenetic Alopecia: Update on Etiology Dermatological reviews · 2021
    7. Therapeutic Use of Botulinum Neurotoxins in Dermatology: Systematic Review Toxins · 2021
    8. Trichoscopic Findings in Androgenetic Alopecia Medicinski arhiv · 2021
    9. A Randomized, Single-Blinded, Vehicle-Controlled Study of a Topical Active Blend in the Treatment of Androgenetic Alopecia Dermatologic Therapy · 2020
    10. Randomized Trial of Electrodynamic Microneedling Combined with 5% Minoxidil Topical Solution for Treating Androgenetic Alopecia in Chinese Males and Molecular Mechanistic Study of the Involvement of the Wnt/β-Catenin Signaling Pathway Journal of Dermatological Treatment · 2020
    11. The Effect of Intradermal Botulinum Toxin on Androgenetic Alopecia and Its Possible Mechanism Journal of The American Academy of Dermatology · 2020
    12. A Review of the Treatment of Male Pattern Hair Loss Expert Opinion on Pharmacotherapy · 2020
    13. Effectiveness and Safety of Botulinum Toxin Type A in the Treatment of Androgenetic Alopecia BioMed Research International · 2020
    14. The Effect of 1540-nm Fractional Erbium-Glass Laser in the Treatment of Androgenic Alopecia Journal of Cosmetic Dermatology · 2019
    15. A Randomized, Investigator-Blinded, Controlled, Split-Scalp Study of the Efficacy and Safety of a 1550-nm Fractional Erbium-Glass Laser, Used in Combination with Topical 5% Minoxidil Versus 5% Minoxidil Alone, for the Treatment of Androgenetic Alopecia Lasers in Medical Science · 2019
    16. A Small Dose of Botulinum Toxin A Is Effective for Treating Androgenetic Alopecia in Chinese Patients Dermatologic Therapy · 2018
    17. A Hypothetical Pathogenesis Model for Androgenic Alopecia: Clarifying the Dihydrotestosterone Paradox and Rate-Limiting Recovery Factors Medical Hypotheses · 2017

    Related research 2

    1. Minoxidil Sulfotransferase Enzymatical Activity in Plants: A Novel Paradigm in Increasing Minoxidil Response in Androgenetic Alopecia Journal of Cosmetic Dermatology · 2023
    2. Scalp Psoriasiform Contact Dermatitis with Acute Telogen Effluvium Due to Topical Minoxidil Treatment Skin appendage disorders · 2015