Efficacy and Safety of JAK Inhibitors in Treating Lichen Planopilaris or Frontal Fibrosing Alopecia

    Chaofan Wang, Yiqun Jiang
    Studysummary This study suggests that Janus kinase inhibitors may offer a potential treatment option for refractory lichen planopilaris and frontal fibrosing alopecia, showing positive response rates between 42% and 100%, though evidence quality is low.
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    Research cited in this study 6

    1. Treatment of Lichen Planopilaris and Frontal Fibrosing Alopecia: A Retrospective, Real-Life Analysis in a Tertiary Center in Germany Journal of Clinical Medicine · 2024
    2. Treatment of Lichen Planopilaris With Janus Kinase Inhibitors Australasian journal of dermatology · 2024
    3. Janus Kinase Inhibition for the Treatment of Refractory Frontal Fibrosing Alopecia: A Case Series and Review of the Literature JAAD Case Reports · 2023
    4. Lichen Planopilaris and Frontal Fibrosing Alopecia: Review and Update of Diagnostic and Therapeutic Features Anais brasileiros de dermatologia/Anais Brasileiros de Dermatologia · 2022
    5. Frontal Fibrosing Alopecia Shows Robust T Helper 1 and Janus Kinase 3 Skewing British journal of dermatology/British journal of dermatology, Supplement · 2020
    6. Tofacitinib for the Treatment of Lichen Planopilaris: A Case Series Dermatologic therapy · 2018

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