Conductive Bio-Harvesting Tonic (CBT) with an Anti-Dandruff Effect Enhances Hair Growth by Utilizing Naturally Generated Electric Energy during Human Activities

    Jisun Kim, Yoonsuk Lee, Jungbum Kim, Chai Won Park, Hyeonhui Song, Jinkee Hong, Sangmin Lee, Won Hee Jung, Joo-Hyun Hong, Ki Hyun Kim, Wonhwa Lee
    TLDR The tonic boosts hair growth and fights dandruff using natural electric energy.
    The study introduces a novel Conductive Bio-Harvesting Tonic (CBT) that enhances hair growth by utilizing naturally generated electric energy from human activities. This tonic incorporates 6-pentyl-α-pyrone (6PP) from *Trichoderma gamsii*, an antifungal agent effective against dandruff-associated fungus *Malassezia*, which can influence alopecia. Testing on hair follicle dermal papilla cells and SKH1 mice showed significant enhancement in hair follicle proliferation and growth factors. In SKH1 mice, CBT application under electric stimulation increased hair shaft length and follicle counts. Human hair follicle tests demonstrated delayed regression with electric stimulation and 6PP. The CBT presents a promising, non-invasive solution for improving hair growth and addressing alopecia.
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