Combination of Candlenut (Aleurites Mollucana (L.) Wild) Oil and Celery (Apium Graveolens) Extract Stimulates Hair Growth: Formulation and Activity Test of Spray Preparation

This study evaluated the efficacy and safety of aerosol formulations containing celery extract and candlenut oil for hair growth stimulation. The formulations were tested at concentrations of 0.1%, 0.5%, and 1% on rabbits. The main fatty acids in candlenut oil were oleic, linoleic, and palmitic acids, while celery extract contained significant amounts of flavonoids and phenolic compounds. The skin irritation test showed no adverse effects, with a primary irritation index of 0.0. The treatment groups showed a significant increase in hair growth compared to the control, with the 1% concentration exhibiting the highest growth rate of 0.64 mm/day. These findings suggest that the combination of celery extract and candlenut oil is an effective and safe natural alternative for treating alopecia.