Bioactive Glass 1393 Promotes Angiogenesis and Accelerates Wound Healing Through ROS/P53/MMP9 Signaling Pathway

This review discusses the use of bioactive glass in skin tissue repair and highlights its potential to aid wound healing through effects on inflammatory cells and tissue regeneration, but reports no new experimental findings.

In this study, the Cu-doped bioglass composite dressings showed promising results for wound healing and hair follicle regeneration in vitro, with enhanced fibroblast proliferation and vascular growth.

This study found that bioactive glass-based camouflage composite particles enhanced the coagulation effects in bleeding models by forming a fibrin network and activating coagulation pathways, suggesting potential use as an emergency hemostasis biomaterial.

This review highlights how silicate-based bioceramics and bioglasses could enhance skin regeneration for wound healing by promoting angiogenesis, stimulating collagen deposition, and providing anti-infection benefits, while also examining their integration with emerging technologies and current applications.

This study reports that using a hydrogel-based therapy that dynamically regulates reactive oxygen species helps achieve skin regeneration in infected wounds, promoting organized dermal architecture with improved hair follicle and blood vessel formation, rather than scar formation.