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GlossaryMatrix Metalloproteinase-9 (MMP9)

enzyme that breaks down extracellular matrix proteins

Matrix Metalloproteinase-9 (MMP-9), also known as gelatinase B, is an enzyme that breaks down the extracellular matrix, which is the network of proteins and molecules surrounding cells. This process is crucial for tissue remodeling, wound healing, and the progression of certain diseases, including cancer and inflammatory conditions. Elevated levels of MMP-9 are often associated with pathological conditions such as chronic inflammation and tumor metastasis.

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research 6-Gingerol Inhibits Hair Cycle via Induction of MMP2 and MMP9 Expression

7 citations, December 2017 in “Anais da Academia Brasileira de Ciências”

6-Gingerol from ginger may slow down hair growth by affecting certain enzymes and growth factors.

research Hair Keratin KRT81 Is Expressed in Normal and Breast Cancer Cells and Contributes to Their Invasiveness

24 citations, April 2017 in “Oncology Reports”

The hair keratin gene KRT81 is found in both normal and breast cancer cells and helps them invade surrounding tissues.

research Effects of Non-Ablative Fractional Erbium Glass Laser Treatment on Gene Regulation in Human Three-Dimensional Skin Models

24 citations, January 2016 in “Lasers in Medical Science”

Erbium glass laser treatment may help with skin remodeling, reduce inflammation, and improve skin cell maturation.

research RNA Sequence Analysis of Dermal Papilla Cells’ Regeneration in 3D Culture

6 citations, October 2020 in “Journal of Cellular and Molecular Medicine”

3D culture helps maintain hair growth cells better than 2D culture and identifies key genes for potential hair loss treatments.

Transcriptome Analysis Reveals an Inhibitory Effect of Dihydrotestosterone-Treated 2D- and 3D-Cultured Dermal Papilla Cells on Hair Follicle Growth

research Transcriptome Analysis Reveals an Inhibitory Effect of Dihydrotestosterone-Treated 2D- and 3D-Cultured Dermal Papilla Cells on Hair Follicle Growth

5 citations, September 2021 in “Frontiers in Cell and Developmental Biology”

Dihydrotestosterone treatment on 2D and 3D-cultured skin cells slows down hair growth by affecting certain genes and could be a potential target for hair loss treatment.

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