Bioactive Glasses: Advancing Skin Tissue Repair Through Multifunctional Mechanisms and Innovations

Bioactive glasses (BGs) are promising materials for enhancing skin tissue repair due to their multifunctional mechanisms, including promoting angiogenesis, regulating inflammation, and supporting wound healing. They are effective in various wound types, such as diabetic ulcers and burns, by stimulating cell migration, enhancing keratinocyte function, and modulating macrophage activity. BGs also exhibit antibacterial properties and can be combined with other materials like hydrogels to improve their effectiveness. Despite their potential, further research is needed to optimize BG formulations for clinical use and to better understand their effects on soft tissue repair and keratinocytes. A study involving 18 patients showed a 95% excellent and good healing rate in the experimental group using BGs, compared to 50% in the control group, highlighting their potential in clinical applications.