Bioactive Glasses: Advancing Skin Tissue Repair Through Multifunctional Mechanisms and Innovations

January 2025 in “ Biomaterials Research ”

Zhi Ren, Shengjie Tang, Jia Wang, Shi-Wen Lv, Kai Zheng, Yong Xu, Ke Li

bioactive glasses skin tissue repair biocompatibility biodegradability antibacterial properties angiogenesis epithelial regeneration collagen deposition scar management

TLDR Bioactive glasses help heal skin wounds by promoting tissue repair and preventing infections.

The review discusses the potential of bioactive glasses (BGs) in skin tissue repair, emphasizing their biological activity, biocompatibility, biodegradability, and antibacterial properties. BGs are shown to regulate inflammatory and tissue repair cells, promoting angiogenesis, inhibiting wound biofilms, and improving inflammatory responses in chronic wounds. They are effective in epithelial regeneration, collagen deposition in burn wounds, and have applications in scar management and post-tumor resection wound care. The review highlights recent advancements in composite materials with BGs and outlines future challenges and directions in BG research for skin tissue regeneration.

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