TLDR Antler stem cell exosomes improve wound healing and reduce scarring.
The study investigates the potential of antler stem cell-derived exosomes (AnSC-exos) in promoting regenerative wound healing. In a rat model, AnSC-exos were applied to full-thickness wounds, resulting in accelerated healing and improved quality, including the regeneration of hair follicles and sebaceous glands, and a basket-weave-like collagen distribution. These effects were more potent than those from bone marrow mesenchymal stem cell-derived exosomes. AnSC-exos also inhibited the fibroblast-to-myofibroblast transition, a key factor in scarring. The findings suggest that AnSC-exos could offer a novel approach for regenerative wound healing in clinical settings.
74 citations
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June 2021 in “Frontiers in Cell and Developmental Biology” Human amniotic fluid stem cell-derived exosomes improve wound healing and reduce scarring.
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August 2019 in “Cells” Mesenchymal stem cells can help repair body tissues with low risk of rejection.
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June 2019 in “Cells” Different fibroblasts play key roles in skin healing and scarring.
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November 2018 in “Nature Communications” The Sonic hedgehog pathway is crucial for new hair growth during mouse skin healing.
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October 2015 in “International journal of molecular sciences” Stem cells are crucial for skin repair and new treatments for chronic wounds.
518 citations
,
November 2014 in “Science” Skin grafting and wound treatment have improved, but we need more research to better understand wound healing and create more effective treatments.
139 citations
,
May 2020 in “Stem Cell Research & Therapy” Exosomes from stem cells help wounds heal faster by affecting specific cell signals.
74 citations
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June 2021 in “Frontiers in Cell and Developmental Biology” Human amniotic fluid stem cell-derived exosomes improve wound healing and reduce scarring.
9 citations
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January 2018 in “Stem Cells International” Deer antler stem cell fluid helps regenerate tissue better than fat-derived stem cell fluid.
1 citations
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October 2023 in “Journal of plastic, reconstructive & aesthetic surgery” Stem cell-derived conditioned medium is effective in improving hair density and thickness for alopecia treatment.
26 citations
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July 2021 in “Frontiers in Cell and Developmental Biology” The review suggests that a special cell-derived treatment shows promise for various skin conditions and hair growth but needs more research for confirmation.
