Antler Stem Cell-Derived Exosomes Promote Regenerative Wound Healing via Fibroblast-to-Myofibroblast Transition Inhibition

    November 2023 in “ Journal of Biological Engineering ”
    Guokun Zhang, Dongxu Wang, Jing Ren … Chunyi Li
    Studysummary This study found that exosomes derived from antler stem cells significantly enhanced wound healing speed and quality in rats, including better skin regeneration and collagen distribution, outperforming exosomes from bone marrow stem cells, and suggesting potential clinical applications.
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    Research cited in this study 6

    1. Human Amniotic Fluid Stem Cell-Derived Exosomes as a Novel Cell-Free Therapy for Cutaneous Regeneration Frontiers in Cell and Developmental Biology · 2021
    2. Mesenchymal Stem Cells for Regenerative Medicine Cells · 2019
    3. Regeneration of Dermis: Scarring and Cells Involved Cells · 2019
    4. Hedgehog Stimulates Hair Follicle Neogenesis by Creating Inductive Dermis During Murine Skin Wound Healing Nature Communications · 2018
    5. Stem Cells in Skin Regeneration, Wound Healing, and Their Clinical Applications International journal of molecular sciences · 2015
    6. Advances in Skin Grafting and Treatment of Cutaneous Wounds Science · 2014