The Topical Penta-Peptide Gly-Pro-Ile-Gly-Ser Increases the Proportion of Thick Hair in Japanese Men with Androgenetic Alopecia

    March 2016 in “ Journal of Cosmetic Dermatology ”
    Tokuro Iwabuchi, Shunsuke Takeda, Haruyo Yamanishi … Syuichi Oka
    Studysummary This study found that the penta-peptide Gly-Pro-Ile-Gly-Ser increased the proportion of thick hair and improved baldness appearance in Japanese men with androgenetic alopecia.
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    Research cited in this study 16

    1. Improvement of Androgenetic Alopecia with Topical Sophora Flavescens Aiton Extract, and Identification of the Two Active Compounds in the Extract That Stimulate Proliferation of Human Hair Keratinocytes Clinical and Experimental Dermatology · 2015
    2. Contribution of Hair Density and Hair Diameter to the Appearance and Progression of Androgenetic Alopecia in Japanese Men British Journal of Dermatology · 2014
    3. L-Ascorbic Acid 2-Phosphate Promotes Elongation of Hair Shafts via the Secretion of Insulin-Like Growth Factor-1 from Dermal Papilla Cells Through Phosphatidylinositol 3-Kinase British journal of dermatology/British journal of dermatology, Supplement · 2009
    4. Adenosine Increases Anagen Hair Growth And Thick Hairs In Japanese Women With Female Pattern Hair Loss: A Pilot, Double-Blind, Randomized, Placebo-Controlled Trial Journal of Dermatology · 2008
    5. Adenosine Stimulates Fibroblast Growth Factor-7 Gene Expression Via Adenosine A2b Receptor Signaling in Dermal Papilla Cells ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2007
    6. A Short Peptide GPIGS Promotes Proliferation of Hair Bulb Keratinocytes and Accelerates Hair Regrowth in Mice Biological & Pharmaceutical Bulletin · 2005
    7. The Chemotactic Effect of a Dermal Papilla Cell-Derived Factor on Outer Root Sheath Cells Journal of Dermatological Science · 2001
    8. Analysis of Apoptotic Cell Death in Human Hair Follicles In Vivo and In Vitro Journal of Investigative Dermatology · 1998
    9. Hair Follicle Elongation in Organ Culture of Skin from Newborn and Adult Mice Journal of Dermatological Science · 1998
    10. Local Injection of Hepatocyte Growth Factor/Scatter Factor Alters Cyclic Growth of Murine Hair Follicles Journal of Investigative Dermatology · 1998
    11. Androgen Induction of Follicular Epithelial Cell Growth Is Mediated via Insulin-like Growth Factor-I from Dermal Papilla Cells Biochemical and biophysical research communications · 1995
    12. Organ Culture of Human Hair Follicles in Serum-Free Medium Archives of Dermatological Research · 1993
    13. Effects of Cepharanthine and Minoxidil on Proliferation, Differentiation, and Keratinization of Cultured Cells from the Murine Hair Apparatus Archives of Dermatological Research · 1992
    14. Human Hair Growth In Vitro Journal of Cell Science · 1990
    15. Minoxidil Stimulates Mouse Vibrissae Follicles in Organ Culture Journal of Investigative Dermatology · 1989
    16. Hypertrichosis Due to Minoxidil British Journal of Dermatology · 1979

    Related research 3

    1. The Topical Penta-Peptide Gly-Pro-Ile-Gly-Ser Increases the Proportion of Thick Hair in Japanese Men with Androgenetic Alopecia Journal of Cosmetic Dermatology · 2016
    2. Improvement of Androgenetic Alopecia with Topical Sophora Flavescens Aiton Extract, and Identification of the Two Active Compounds in the Extract That Stimulate Proliferation of Human Hair Keratinocytes Clinical and Experimental Dermatology · 2015
    3. Characterization of Hair Follicle Development in Engineered Skin Substitutes PLOS ONE · 2013