Sympathetic Reinnervation of Intact and Upper Follicle Xenografts into BALB/c-nu/nu Mice

November 2023 in “ Life ”

Xiu-Wen Chen, Na Ni, Xiaojun Xie, Yinglin Zhao, Wen‐Miin Liang, Yuxin Huang, Cheng Huang Lin

sympathetic nerves hair growth transplantation vibrissa follicles BALB/c-nu/nu mice anagen phase tyrosine-hydroxylase-positive nerves norepinephrine sympathetic reinnervation xenografts whisker follicles growth phase sympathetic nerves marker sympathetic nerve restoration grafts

Studysummary In this study, rat vibrissa follicles transplanted into mice demonstrated survival, partial sympathetic nerve reinnervation, and increased norepinephrine levels 37 days post-implantation, suggesting potential for hair growth despite not returning to normal nerve function.

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