32 citations
,
March 2013 in “Journal of Pharmaceutical Sciences” This study observed that iontophoresis significantly improved the delivery of minoxidil sulfate to hair follicles compared to passive methods, suggesting potential benefits for alopecia treatment.
58 citations
,
September 2012 in “Dermatologic Clinics” This article reviews current knowledge on the causes, diagnosis, and medical treatments for androgenetic alopecia, particularly in men, and reports no new findings.
263 citations
,
February 2011 in “Journal of Controlled Release” This study found that medium-sized particles (643 and 646 nm) penetrated deeper into porcine hair follicles in vitro than smaller or larger particles, suggesting size-selective targeting within follicular sites.
49 citations
,
September 2008 in “International journal of pharmaceutics” This study suggests that artificial sebum L may serve as an effective substitute for human sebum in drug transport studies, due to its similar physicochemical properties.
19 citations
,
January 2008 in “Journal of Pharmacy and Pharmacology” This study found that porcine skin serves as a reliable model for studying drug absorption into human hair follicles, showing a strong correlation in follicular drug absorption between porcine and human skin.
162 citations
,
August 2005 in “The journal of investigative dermatology/Journal of investigative dermatology” This study introduces a novel non-invasive method called "differential stripping" to quantify the penetration of topically applied substances into hair follicles.
405 citations
,
January 2004 in “Journal of Investigative Dermatology” This study found that hair follicle characteristics vary significantly across different body sites, with the forehead and calf showing the highest potential follicular reservoirs, challenging previous assumptions about skin appendage distribution.
47 citations
,
September 1997 in “Journal of Pharmaceutical Sciences” This study found that cationic lipid-based formulations enhanced the delivery of large molecules into hair follicles in human scalp skin, with potential to reach pharmacologically active concentrations in the hair bulb.