A Systematic Study of Determination and Validation of Finasteride Impurities Using Liquid Chromatography

    January 2019 in “ Arabian Journal of Chemistry ”
    Aysen Kurt Cucu, Serap Sakarya, Hülya Demir, Sarfraz Ahmad
    Studysummary This study developed and validated an HPLC method to quantify impurities in finasteride, demonstrating its suitability for quality assurance of the drug and its related substances.
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    Research cited in this study 8

    1. Development and Validation of a New Gas Flame Ionization Detector Method for the Determination of Finasteride in Tablets Analytical Biochemistry · 2006
    2. Determination of Finasteride in Tablet Form by Liquid Chromatography and Its Analytical Method Validation Analytica Chimica Acta · 2006
    3. Polarographic Behavior and Determination of Finasteride Farmaco · 2003
    4. Determination of Finasteride in Human Plasma by Liquid-Liquid Extraction and High-Performance Liquid Chromatography Journal of Chromatography B: Biomedical Sciences and Applications · 2000
    5. High-Performance Liquid Chromatographic Determination of Finasteride in Human Plasma Using Direct Injection with Column Switching Journal of Chromatography B: Biomedical Sciences and Applications · 1996
    6. Synthesis of 5,6,6-[2H3]Finasteride and Quantitative Determination of Finasteride in Human Plasma at Picogram Level by an Isotope-Dilution Mass Spectrometric Method Journal of Chromatography B: Biomedical Sciences and Applications · 1995
    7. Picogram Determination of Finasteride in Human Plasma and Semen by High-Performance Liquid Chromatography with Atmospheric-Pressure Chemical-Ionization Tandem Mass Spectrometry Journal of Chromatography B: Biomedical Sciences and Applications · 1994
    8. The Effect of Finasteride in Men with Benign Prostatic Hyperplasia The New England Journal of Medicine · 1992

    Related research 1

    1. Sensitive Bromatometric Determination of Finasteride in Pharmaceuticals Based on Complex-Formation Reactions Analytical chemistry, an Indian journal · 2006