Hair Loss: An Overlooked Nonmotor Symptom in Parkinson’s Disease During Dopaminergic Therapy

    September 2023 in “ Journal of movement disorders ”
    Jungyeun Lee, Hwa Jung Ryu, Soon Young Hwang, Seong‐Beom Koh
    Studysummary In this study, 27.9% of Parkinson's disease patients reported hair loss, with a higher incidence linked to a daily levodopa-equivalent dose over 448 mg, suggesting an association between dopaminergic medication use and hair loss complaints.
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    Research cited in this study 16

    1. Diagnosis and Treatment of Nonscarring Hair Loss in Primary Care in 2021 JAMA · 2021
    2. Telogen Effluvium: A Review of the Science and Current Obstacles Journal of Dermatological Science · 2021
    3. Hair Pull Test: A Clinical Update for Patients with Asian- and Afro-Textured Hair Journal of the American Academy of Dermatology · 2020
    4. Hormonal Effects on Hair Follicles International journal of molecular sciences · 2020
    5. Hair Biology Facial Plastic Surgery Clinics of North America · 2018
    6. Hair Pull Test: Evidence-Based Update and Revision of Guidelines Journal of The American Academy of Dermatology · 2016
    7. Neuroendocrinology of the Hair Follicle: Principles and Clinical Perspectives Trends in Molecular Medicine · 2014
    8. Dopamine Is a Novel, Direct Inducer of Catagen in Human Scalp Hair Follicles In Vitro British Journal of Dermatology · 2012
    9. Utilizing the Hair Follicle to Dissect the Regulation and Autocrine/Paracrine Activities of Prolactin in Humans Endocrinology and metabolism/American journal of physiology: endocrinology and metabolism · 2012
    10. S1 Guideline for Diagnostic Evaluation in Androgenetic Alopecia in Men, Women, and Adolescents British Journal of Dermatology · 2010
    11. Mind the Gender Gap: Does Prolactin Exert Gender and Site-Specific Effects on the Human Hair Follicle? Journal of Investigative Dermatology · 2009
    12. Hair Evaluation Methods: Merits and Demerits International Journal of Trichology · 2009
    13. Assessment of Hair Loss: Clinical Relevance of Hair Growth Evaluation Methods Clinical and Experimental Dermatology · 2002
    14. Alopecia Induced by Dopamine Agonists Neurology · 2002
    15. The Psychology of Hair Loss and Its Implications for Patient Care Clinics in Dermatology · 2001
    16. Classification of the Types of Androgenetic Alopecia (Common Baldness) Occurring in the Female Sex British Journal of Dermatology · 1977

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    2. Safety and Efficacy of Trimax-360 Serum in Healthy Adult Subjects with Mild to Moderate Alopecia of the Scalp Journal of Cosmetic Dermatology · 2022
    3. Significant Relationship Between Temporal Hair Loss and Other Scalp Areas in Female Pattern Hair Loss Journal of Dermatology · 2020
    4. The Changing Patterns of Hair Density and Thickness in South Korean Women with Hair Loss: Clinical Office-Based Phototrichogram Analysis International Journal of Dermatology · 2008