Efficacy of Bimatoprost in Treating Chemotherapy-Induced Milphosis: A Comprehensive Review of Randomized Controlled Trials

    March 2025 in “ JAAD reviews.
    Simonetta I. Gaumond, Peyton V. Warp, Rama Abdin, Joaquín J. Jiménez
    Studysummary This review found that bimatoprost effectively treats chemotherapy-induced eyelash loss, known as milphosis, in cancer patients, as demonstrated in three small trials, but further research is needed due to limitations like small sample sizes and short follow-up periods.
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    Research cited in this study 15

    1. From Eye Care to Hair Growth: Bimatoprost Pharmaceuticals · 2024
    2. Impact and Management of Loss of Eyebrows and Eyelashes Dermatology and therapy · 2023
    3. Eyebrow and Eyelash Alopecia: A Clinical Review American journal of clinical dermatology · 2022
    4. Madarosis: A Qualitative Study to Assess Perceptions and Experience of Australian Patients with Early Breast Cancer Treated with Taxane-Based Chemotherapy Supportive care in cancer · 2017
    5. Madarosis, Milphosis, Eyelash Trichomegaly, and Dermatochalasis: Conditions Affecting the Periocular Area Clinics in Dermatology · 2015
    6. Bimatoprost Versus Mometasone Furoate in the Treatment of Scalp Alopecia Areata: A Pilot Study Dermatology · 2015
    7. Long-Term Safety and Efficacy of Bimatoprost Solution 0.03% Application to the Eyelid Margin for the Treatment of Idiopathic and Chemotherapy-Induced Eyelash Hypotrichosis: A Randomized Controlled Trial British journal of dermatology/British journal of dermatology, Supplement · 2014
    8. Treatment of Chemotherapy-Induced Alopecia Dermatologic Therapy · 2011
    9. Enhancing the Growth of Natural Eyelashes: The Mechanism of Bimatoprost-Induced Eyelash Growth Dermatologic Surgery · 2010
    10. Management of Hypotrichosis of the Eyelashes: Focus on Bimatoprost Clinical, cosmetic and investigational dermatology · 2010
    11. Characterization of an In Vivo Model for the Study of Eyelash Biology and Trichomegaly: Mouse Eyelash Morphology, Development, Growth Cycle, and Anagen Prolongation by Bimatoprost British journal of dermatology/British journal of dermatology, Supplement · 2010
    12. Instilled Bimatoprost Ophthalmic Solution in Patients with Eyelash Alopecia Areata Journal of the American Academy of Dermatology · 2009
    13. Androgens and Hair Growth Dermatologic Therapy · 2008
    14. Madarosis Survey of Ophthalmology · 2006
    15. Assessment of Rate of Hair Growth Using a Simple Trichometer Medical & biological engineering & computing · 1979

    Related research 1

    1. The Biodisposition and Hypertrichotic Effects of Bimatoprost in Mouse Skin Experimental dermatology · 2013