Keratin Function and Regulation in Tissue Homeostasis and Pathogenesis

    April 2012 in “ Biomolecular concepts ”
    Wera Roth, Meçhthild Hatzfeld, M. Friedrich … Thomas M. Magin
    Studysummary This article reviews the role of keratins in epithelial function and structure, discussing their involvement in growth control, organelle functions, and pathomechanisms of disorders, but reports no new clinical results.
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    Research cited in this study 5

    1. Epidermolysis Bullosa Simplex: A Paradigm for Disorders of Tissue Fragility ˜The œJournal of clinical investigation/˜The œjournal of clinical investigation · 2009
    2. The Human Keratins: Biology And Pathology Histochemistry and Cell Biology · 2008
    3. Vibrissa Hair Bulge Houses Two Populations of Skin Epithelial Stem Cells Distinct by Their Keratin Profile ˜The œFASEB journal · 2007
    4. Keratin 17 Modulates Hair Follicle Cycling in a TNFα-Dependent Fashion Genes & Development · 2006
    5. Exploiting the Keratin 17 Gene Promoter to Visualize Live Cells in Epithelial Appendages of Mice Molecular and Cellular Biology · 2005