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    Low-Dose In Utero Exposure to Finasteride Promotes Developmental Changes in Both Male and Female Gerbil Prostates

    August 2019 in “ Environmental Toxicology ”
    Juliana S. Maldarine, Bruno Domingos Azevedo Sanches, Vitória A. Santos … Sebastião Roberto Taboga
    Studysummary This study observed that low-dose intrauterine exposure to finasteride alters postnatal prostate development in male and female Mongolian gerbils, showing sex-specific differences in receptor expression and tissue changes.
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    Research cited in this study 9

    1. Evaluation of the 5α-Reductase Inhibitor Finasteride on Reproduction and Gonadal Development in Medaka, Oryzias Latipes General and Comparative Endocrinology · 2015
    2. Photostability and Toxicity of Finasteride, Diclofenac, and Naproxen Under Simulated Sunlight Exposure: Evaluation of the Toxicity Trend and Packaging Photoprotection Chemistry Central Journal · 2013
    3. A Multi-Technique Approach to the Study of Structural Stability and Desolvation of Two Unusual Channel Hydrate Solvates of Finasteride Journal of Pharmaceutical Sciences · 2011
    4. An Overview on 5α-Reductase Inhibitors Steroids · 2009
    5. The Aromatase Inhibitor Fadrozole and the 5-Reductase Inhibitor Finasteride Affect Gonadal Differentiation and Gene Expression in the Frog Silurana Tropicalis Sexual Development · 2009
    6. A New Look at the 5-Alpha-Reductase Inhibitor Finasteride Cns Drug Reviews · 2006
    7. Use of Finasteride in the Treatment of Men With Androgenetic Alopecia Journal of Investigative Dermatology Symposium Proceedings · 2003
    8. Effects of In Utero Exposure to Finasteride on Androgen-Dependent Reproductive Development in Male Rats Toxicological Sciences · 2003
    9. The Benefits of Finasteride for Hirsute Women with Polycystic Ovary Syndrome or Idiopathic Hirsutism Gynecological Endocrinology · 2003