Therapeutic Efficacy and Promise of Human Umbilical Cord Mesenchymal Stem Cell-Derived Extracellular Vesicles in Aging and Age-Related Disorders

    December 2024 in “ International Journal of Molecular Sciences ”
    Anyuan Zhang, Qiubai Li, Zhichao Chen
    Studysummary This study provides a comprehensive overview of human umbilical cord mesenchymal stem cell-derived extracellular vesicles (HUCMSC-EVs), suggesting their potential to combat aging and alleviate age-related disorders by rejuvenating multiple organs in animal models and discussing engineering strategies to harness their full anti-aging potential.
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    Research cited in this study 2

    1. Extracellular Vesicles as Human Therapeutics: A Scoping Review of the Literature Journal of Extracellular Vesicles · 2024
    2. Umbilical Cord Mesenchymal Stem Cell-Derived Apoptotic Extracellular Vesicles Ameliorate Cutaneous Wound Healing in Type 2 Diabetic Mice via Macrophage Pyroptosis Inhibition Stem cell research & therapy · 2023