Review of Stem Cell Therapy for Hair Loss

July 2024 in “ Journal of Dermatology Research Reviews & Reports ”

Humoud Mansour Alkhalaf, Hatim Sahil Alotaibi, Mohammad Alzaid, Abdullah Baqayis, Ashwaq Almutairi

stem cell therapy androgenetic alopecia hair follicle stem cells stem cell transplants conditioned media exosomes hair follicle development stem cell treatment hair loss hair growth

Studysummary This study reviews the potential of stem cell-based therapies, including transplants and exosome treatments, to reactivate hair follicle stem cells and promote hair growth in individuals experiencing pattern hair loss.

Our plain-language summary. Not medical advice or a treatment recommendation. Consult a qualified healthcare professional before changing treatment. Full disclaimer

Stem cell therapy has emerged as a promising treatment for hair loss, particularly androgenetic alopecia, by aiming to reactivate hair follicle stem cells to promote hair growth and regeneration. Techniques include stem cell transplants, conditioned media derived from stem cells, and exosomes from stem cells. These methods have shown potential in advancing hair follicle development and addressing hair loss in both males and females.

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research Stem Cell Applications in Human Hair Growth: A Literature Review

8 citations , April 2023 in “Cureus”

This review explores stem cell applications for hair regrowth in alopecia, with no new clinical results, suggesting potential advantages over current FDA-approved treatments.

research Advances in Stem Cell-Based Therapy for Hair Loss

7 citations , January 2020 in “PubMed”

In this review, researchers highlight preclinical and clinical studies on stem cell-based therapies for hair loss, noting promising early findings but indicating that further robust clinical research is necessary to better understand their effectiveness, safety, and mechanisms.

research Stem Cell Therapy and Hair Loss: Present Evidence and Future Perspectives

1 citations , July 2019 in “Journal of Dermatology and Dermatologic Surgery”

This review discusses the potential of stem cell therapies for regenerating hair in nonautoimmune hair loss and calls for more studies to evaluate their efficacy.

research Therapeutic Potential of Stem Cells in Follicle Regeneration

45 citations , August 2018 in “Stem Cells International”

This article reviews the potential of adipose-derived and Wharton’s jelly stem cells in alopecia treatment but presents no new clinical findings, highlighting their potential benefits and limitations in regenerative medicine.

research Self-Organization Process in Newborn Skin Organoid Formation Inspires Strategy to Restore Hair Regeneration of Adult Cells

92 citations , August 2017 in “Proceedings of the National Academy of Sciences of the United States of America”

This study found that newborn mouse skin organoids can robustly grow hair in vivo, while adult organoids require specific interventions to restore their hair-forming ability.

Stem Cells from Human Hair Follicles: First Mechanical Isolation for Immediate Autologous Clinical Use in Androgenetic Alopecia and Hair Loss

research Stem Cells from Human Hair Follicles: First Mechanical Isolation for Immediate Autologous Clinical Use in Androgenetic Alopecia and Hair Loss

86 citations , June 2017 in “Stem cell investigation”

This study reported that using human follicle stem cells isolated from hair bulge areas increased hair density by about 29% over baseline in patients with androgenetic alopecia, with significant improvements observed 23 weeks after the last treatment.

research Stem Cell Therapy as a Novel Therapeutic Intervention for Resistant Cases of Alopecia Areata and Androgenetic Alopecia

39 citations , August 2016 in “Journal of Dermatological Treatment”

This study observed that autologous bone marrow derived mononuclear cells and follicular stem cells were both safe and effective for improving resistant alopecia areata and androgenetic alopecia, with no serious adverse events.

research Hair Regrowth in Alopecia Areata Patients Following Stem Cell Educator Therapy

55 citations , April 2015 in “BMC medicine”

This study found that the Stem Cell Educator therapy improved hair regrowth and quality of life in patients with severe alopecia areata by restoring immune balance and protecting hair follicles from autoimmune damage.

research Clinical Use of Conditioned Media of Adipose Tissue-Derived Stem Cells in Female Pattern Hair Loss: A Retrospective Case Series Study

83 citations , March 2015 in “International Journal of Dermatology”

This retrospective study found that adipose-derived stem cell-conditioned media increased hair density and thickness in women with female pattern hair loss over 12 weeks, with no severe adverse effects reported.

research Adipose Derived Stem Cells and Growth Factors Applied in Hair Transplantation: Follow-Up of Clinical Outcome

20 citations , January 2014 in “Journal of Cosmetics, Dermatological Sciences and Applications”

This study suggests that applying a suspension of adipose-derived cells during hair transplantation may enhance wound healing and promote continued hair growth shortly after the procedure.