The Phytocannabinoid (–)-Cannabidiol Operates as a Complex, Differential Modulator of Human Hair Growth: Anti-Inflammatory Submicromolar Versus Hair Growth Inhibitory Micromolar Effects

July 2019 in “ Journal of Investigative Dermatology ”

Imre Szabó, Erika Lorenzetto, Gabriella Béke, Kinga Fanni Tóth, Ralf Paus, Attila Oláh, Tamás Bı́ró

Cannabidiol CBD hair growth outer root sheath keratinocytes ORSKs anti-inflammatory catagen calcium influx apoptosis inflammatory hair loss disorders hair follicles hair loss

Studysummary This exploratory study found that cannabidiol (CBD) at higher concentrations may inhibit hair growth by promoting the onset of catagen in human hair follicles, while lower concentrations showed potential anti-inflammatory effects without promoting catagen.

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