research Restructuring skin equivalents with human hair follicle orscs and fibroblasts
A new method was developed to create better skin models for healing and reconstruction.
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5 / 141 resultsresearch 083 The effect of topical hair growth promoters on internal calcium of human outer root sheath cells(ORSCs)
research Epithelial–mesenchymal transition in keloid tissues and TGF‐β1–induced hair follicle outer root sheath keratinocytes
This study found that keloid tissues exhibit epithelial-mesenchymal transition-related changes and alterations in gene expression, implicating these processes in the pathogenesis of keloids.
research The Phytocannabinoid (–)-Cannabidiol Operates as a Complex, Differential Modulator of Human Hair Growth: Anti-Inflammatory Submicromolar versus Hair Growth Inhibitory Micromolar Effects
This exploratory study found that cannabidiol (CBD) at higher concentrations may inhibit hair growth by promoting the onset of catagen in human hair follicles, while lower concentrations showed potential anti-inflammatory effects without promoting catagen.
research S100A8 induces cyclophosphamide-induced alopecia via NCF2/NOX2-mediated ferroptosis
In a mouse model of chemotherapy-induced alopecia, this study found that inhibiting the protein S100A8 with paquinimod alleviated hair loss and reduced oxidative stress and ferroptosis, suggesting a potential therapeutic strategy for managing this side effect in chemotherapy patients.
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