Localization of Skin Stem Cells of Inner Mongolia Cashmere Goats

January 2009 in “ Hubei nongye kexue ”

XI Hai-yana

skin stem cells hair follicles epidermis BrdU labeling dermal papilla collagen IV G0/G1 phase

Studysummary This study identified stem cells in the primary and secondary hair follicles and epidermis of Inner Mongolia cashmere goats, with BrdU labeling proving effective for up to 10 weeks.

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The study investigated the localization of skin stem cells in Inner Mongolia cashmere goats, focusing on primary and secondary hair follicles and the epidermis. By using BrdU labeling, researchers confirmed the presence of stem cells in these areas, with BrdU remaining detectable for up to 10 weeks. The study found that stem cells were located in the dermal papilla of hair follicles, which exhibited unlimited proliferative capacity when cultivated with collagen IV. These stem cells were characterized by their round or polygonal shape, large nuclei, and slow cell cycle, with a significant percentage (73.98%±4.74%) of cells in the G0/G1 phase, indicating a slow proliferation rate.

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