A Hot New Twist to Hair Biology: The Role of TRPV1 in Human Hair Growth Control

April 2005 in “ The American journal of pathology (Print) ”

Enikő Bodó, Tamás Bı́ró, Andrea Telek, Gabriella Czifra, Zoltán Griger, Balázs Tóth, Alessandra Mescalchin, Taisuke Ito, Albrecht Bettermann, László Kovács, Ralf Paus

vanilloid receptor-1 TRPV1 capsaicin hair follicle hair shaft elongation cell proliferation apoptosis hair follicle regression transforming growth factor-ß₂ TGF-B₂ hair growth inhibitor

Studysummary This study found that TRPV1 activation in human scalp hair follicles inhibited hair shaft elongation, suppressed proliferation, and induced apoptosis, suggesting TRPV1 as a potential target for managing hair growth and epithelial disorders.

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