6 citations
,
February 2010 in “Biotechnology and bioprocess engineering” This study investigated optimizing the differentiation process of UC-MSCs into dermal papilla-like tissues for potential hair follicle therapy and highlighted the potential to reduce associated costs by evaluating cell density and growth factors.
44 citations
,
June 2009 in “Biomaterials” In this study, fibronectin coating on a low-adhesive substratum increased cell aggregation, growth, and motility, enhancing the formation of hair follicle dermal papilla spheroids.
34 citations
,
March 2009 in “British journal of dermatology/British journal of dermatology, Supplement” In this study, l-Ascorbic acid 2-phosphate was found to stimulate hair follicle growth in vitro by promoting IGF-1 expression via the PI3K pathway.
24 citations
,
February 2006 in “Chinese Medical Journal” This study found that dermal papilla cells cultured in vitro can promote hair follicle regeneration and maintain hair growth, with stronger ET-1 and SCF expression enhancing this regenerative ability.
88 citations
,
May 2005 in “Journal of Dermatological Science” In this study, specific versican expression was observed in the anagen phase of human hair follicles, suggesting its importance in maintaining normal hair growth.
57 citations
,
November 1998 in “Wound Repair and Regeneration” This research observed that dermal papilla cells have the potential to regenerate hair bulbs under preferred environmental conditions when associated with dermal sheath cells or exposed to specific growth factors.
19 citations
,
October 1996 in “Dermatologic Clinics” This review discusses using cultured dermal papilla cells to investigate hair follicle biology, emphasizing their potential to inform treatments, but reports no new clinical results.
