Minoxidil Upregulates the Expression of Vascular Endothelial Growth Factor in Human Hair Dermal Papilla Cells

    March 1998 in “ British Journal of Dermatology ”
    S. Lachgar, Marie Charveron, Y. Gall, Bonafé Jl
    Studysummary This study found that minoxidil significantly increases VEGF mRNA and protein expression in dermal papilla cells, suggesting a role in enhancing hair follicle vascularization in androgenetic alopecia.
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    Research cited in this study 4

    1. Inhibitory Effects of bFGF, VEGF, and Minoxidil on Collagen Synthesis by Cultured Hair Dermal Papilla Cells Archives of Dermatological Research · 1996
    2. Vascular Endothelial Growth Factor Is an Autocrine Growth Factor for Hair Dermal Papilla Cells Journal of Investigative Dermatology · 1996
    3. Immunolocalization of Epidermal Growth Factor Receptors in Normal Developing Human Skin Journal of Investigative Dermatology · 1990
    4. Topical Minoxidil in Early Male Pattern Baldness Journal of The American Academy of Dermatology · 1985

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    9. Minoxidil Upregulates the Expression of Vascular Endothelial Growth Factor in Human Hair Dermal Papilla Cells British Journal of Dermatology · 1998
    10. Vascular Endothelial Growth Factor Is an Autocrine Growth Factor for Hair Dermal Papilla Cells Journal of Investigative Dermatology · 1996