Stabilization of Hemidesmosomal Proteins: A Possible Key Contributor to Wnt/β-Catenin Pathway Action in the Skin

    December 2021 in “ Journal of Investigative Dermatology ”
    Sho Hiroyasu, Daisuke Tsuruta
    Studysummary This study reports that inhibition of Wnt/β-catenin signaling disrupts hemidesmosome organization in keratinocytes by altering the localization of components like plectin and collagen XVII.
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    Research cited in this study 6

    1. Wnt/β-Catenin Signaling Stabilizes Hemidesmosomes in Keratinocytes ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2021
    2. Concise Review: Wnt Signaling Pathways in Skin Development and Epidermal Stem Cells Stem cells · 2017
    3. Type XVII Collagen Coordinates Proliferation in the Interfollicular Epidermis eLife · 2017
    4. Wnt and Notch Signaling Pathway Involved in Wound Healing by Targeting c-Myc and Hes1 Separately Stem Cell Research & Therapy · 2015
    5. Coordinated Activation of Wnt in Epithelial and Melanocyte Stem Cells Initiates Pigmented Hair Regeneration Cell · 2011
    6. Hair Follicle Stem Cells Provide a Functional Niche for Melanocyte Stem Cells Cell stem cell · 2011